Misfortune
Misfortune (noun) /ˌmɪsˈfɔː.tʃuːn/ US /-ˈfɔːr.tʃən/
bad luck – ill luck – unlucky event, tribulation, misadventure, calamity, catastrophe, disaster
I had the misfortune of selling my house at a low price when I desperately had to do so.
Antonym: opportunity